Characteristics of contrast processing deficits in X-linked retinoschisis

Characteristics of contrast processing deficits in X-linked retinoschisis

Contrast sensitivity and contrast discrimination were evaluated in six males with X-linked retinoschisis (XLRS), a form of early-onset macular degeneration, using testing paradigms designed to favor either the magnocellular (MC) or parvocellular (PC) pathway. Compared to a group of age-similar control observers, the patients with XLRS showed a pronounced loss of contrast sensitivity at high spa...

Molecular genetic characteristics of X-linked retinoschisis in Koreans

PURPOSE X-linked retinoschisis (XLRS) is a recessively inherited disorder that causes macular degeneration and resultant visual defect in young males. Many genetic studies had focused on the patients in Western countries. We characterized the mutational spectrum of the RS1 gene in Korean patients with XLRS, and aimed to provide genetic information of XLRS in an Asian population. METHODS This ...

X-linked Hereditary Retinoschisis.

AN X-linked degenerative retino-choroidal disease, hereditary retinoschisis, has been identified in the last 10 years. In milder cases the disease takes the form of radial macular degeneration, but in severe cases a grey sheet-like veil is attached to the detachment in the retinal vasculature, especially in the lower temporal quadrant. In differential diagnosis, according to Ricci (1960), a dom...

X linked retinoschisis.

X-linked Juvenile Retinoschisis

Keywords Diagnostic criteria/definition Synonyms Historical overview Excluded diseases Differential diagnosis Prevalence Clinical description Evolution Treatment Etiology Diagnostic methods Genetics Genetic counseling Prenatal diagnosis References Abstract X-linked retinoschisis is a congenital ocular disease secondary to an abnormal cleavage of the innermost layer of the retina. The frequency ...